Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months

A Meretoja; L Weir; M Ugalde; N Yassi; B Yan; P Hand; M Truesdale; SM Davis; BCV Campbell

Journal article

Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months

A Meretoja, L Weir, M Ugalde, N Yassi, B Yan, P Hand, M Truesdale, SM Davis, BCV Campbell

Neurology | Published : 2013

DOI: 10.1212/WNL.0b013e3182a4a4d2

Abstract

Objective: To test the transferability of the Helsinki stroke thrombolysis model that achieved a median 20-minute door-to-needle time (DNT) to an Australian health care setting. Methods: The existing "code stroke" model at the Royal Melbourne Hospital was evaluated and restructured to include key components of the Helsinki model: 1) ambulance prenotification with patient details alerting the stroke team to meet the patient on arrival; 2) patients transferred directly from triage onto the CT table on the ambulance stretcher; and 3) tissue plasminogen activator (tPA) delivered in CT immediately after imaging. We analyzed our prospective, consecutive tPA registry for effects of these protocol c..

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University of Melbourne Researchers

Nawaf Yassi Author

Bernard Yan Author

Melinda Truesdale Author

Stephen Davis Author

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Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC) Centre for Research Excellence grant

Awarded by NHMRC Early Career Fellowship

Funding Acknowledgements

Supported by the National Health and Medical Research Council of Australia (NHMRC) Centre for Research Excellence grant 1001216. The authors received additional support from Finnish Medical, Biomedicum Helsinki, and Sigrid Juselius Foundations (A. M.), University of Melbourne, and Neurosciences Victoria (N.Y.), NHMRC Early Career Fellowship 1035688, Heart Foundation of Australia, National Stroke Foundation, and Cardiovascular Lipid Australia (B. C. V. C), and The Royal Melbourne Hospital Neurosciences Foundation (N.Y., B.C.V.C).